AI Bibliography
AI Bibliography |
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Kriegman, S., Blackiston, D., Levin, M., & Bongard, J. (2021). Kinematic self-replication in reconfigurable organisms. Proceedings of the National Academy of Sciences, 118(49). |
| Resource type: Journal Article DOI: 10.1073/pnas.2112672118 ID no. (ISBN etc.): 0027-8424 BibTeX citation key: Kriegman2021 View all bibliographic details  |
Categories: Artificial Intelligence, Biological Science, Computer Science, Engineering, General, Geopolitical, Medical science, Nanotechnology Subcategories: Autonomous systems, Nanotechnology, Robotics, United States Creators: Blackiston, Bongard, Kriegman, Levin Publisher: Collection: Proceedings of the National Academy of Sciences |
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Almost all organisms replicate by growing and then shedding offspring. Some molecules also replicate, but by moving rather than growing: They find and combine building blocks into self-copies. Here we show that clusters of cells, if freed from a developing organism, can similarly find and combine loose cells into clusters that look and move like they do, and that this ability does not have to be specifically evolved or introduced by genetic manipulation. Finally, we show that artificial intelligence can design clusters that replicate better, and perform useful work as they do so. This suggests that future technologies may, with little outside guidance, become more useful as they spread, and that life harbors surprising behaviors just below the surface, waiting to be uncovered.All living systems perpetuate themselves via growth in or on the body, followed by splitting, budding, or birth. We find that synthetic multicellular assemblies can also replicate kinematically by moving and compressing dissociated cells in their environment into functional self-copies. This form of perpetuation, previously unseen in any organism, arises spontaneously over days rather than evolving over millennia. We also show how artificial intelligence methods can design assemblies that postpone loss of replicative ability and perform useful work as a side effect of replication. This suggests other unique and useful phenotypes can be rapidly reached from wild-type organisms without selection or genetic engineering, thereby broadening our understanding of the conditions under which replication arises, phenotypic plasticity, and how useful replicative machines may be realized.
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